Antigenicity analysis of different regions of the severe acute respiratory syndrome coronavirus nucleocapsid protein.
Identifieur interne : 005458 ( Main/Exploration ); précédent : 005457; suivant : 005459Antigenicity analysis of different regions of the severe acute respiratory syndrome coronavirus nucleocapsid protein.
Auteurs : Zeliang Chen [République populaire de Chine] ; Decui Pei ; Lingxiao Jiang ; Yajun Song ; Jin Wang ; Hongxia Wang ; Dongsheng Zhou ; Junhui Zhai ; Zongmin Du ; Bei Li ; Maofeng Qiu ; Yanping Han ; Zhaobiao Guo ; Ruifu YangSource :
- Clinical chemistry [ 0009-9147 ] ; 2004.
Descripteurs français
- KwdFr :
- ADN complémentaire (génétique), Analyse par réseau de protéines, Antigènes viraux (génétique), Antigènes viraux (immunologie), Clonage moléculaire, Escherichia coli (métabolisme), Humains, Protéines nucléocapside (biosynthèse), Protéines nucléocapside (génétique), Protéines nucléocapside (immunologie), Syndrome respiratoire aigu sévère (diagnostic), Virus du SRAS (immunologie), Virus du SRAS (isolement et purification), Épitopes.
- MESH :
- biosynthèse : Protéines nucléocapside.
- diagnostic : Syndrome respiratoire aigu sévère.
- génétique : ADN complémentaire, Antigènes viraux, Protéines nucléocapside.
- immunologie : Antigènes viraux, Protéines nucléocapside, Virus du SRAS.
- isolement et purification : Virus du SRAS.
- métabolisme : Escherichia coli.
- Analyse par réseau de protéines, Clonage moléculaire, Humains, Épitopes.
English descriptors
- KwdEn :
- Antigens, Viral (genetics), Antigens, Viral (immunology), Cloning, Molecular, DNA, Complementary (genetics), Epitopes, Escherichia coli (metabolism), Humans, Nucleocapsid Proteins (biosynthesis), Nucleocapsid Proteins (genetics), Nucleocapsid Proteins (immunology), Protein Array Analysis, SARS Virus (immunology), SARS Virus (isolation & purification), Severe Acute Respiratory Syndrome (diagnosis).
- MESH :
- chemical , biosynthesis : Nucleocapsid Proteins.
- chemical , genetics : Antigens, Viral, DNA, Complementary, Nucleocapsid Proteins.
- chemical , immunology : Antigens, Viral, Nucleocapsid Proteins.
- diagnosis : Severe Acute Respiratory Syndrome.
- immunology : SARS Virus.
- isolation & purification : SARS Virus.
- metabolism : Escherichia coli.
- Cloning, Molecular, Epitopes, Humans, Protein Array Analysis.
Abstract
The widespread threat of severe acute respiratory syndrome (SARS) to human health has made urgent the development of fast and accurate analytical methods for its early diagnosis and a safe and efficient antiviral vaccine for preventive use. For this purpose, we investigated the antigenicity of different regions of the SARS coronavirus (SARS-CoV) nucleocapsid (N) protein.
DOI: 10.1373/clinchem.2004.031096
PubMed: 15054081
Affiliations:
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Le document en format XML
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populaire de Chine</country><wicri:regionArea>Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Pei, Decui" sort="Pei, Decui" uniqKey="Pei D" first="Decui" last="Pei">Decui Pei</name></author><author><name sortKey="Jiang, Lingxiao" sort="Jiang, Lingxiao" uniqKey="Jiang L" first="Lingxiao" last="Jiang">Lingxiao Jiang</name></author><author><name sortKey="Song, Yajun" sort="Song, Yajun" uniqKey="Song Y" first="Yajun" last="Song">Yajun Song</name></author><author><name sortKey="Wang, Jin" sort="Wang, Jin" uniqKey="Wang J" first="Jin" last="Wang">Jin Wang</name></author><author><name sortKey="Wang, Hongxia" sort="Wang, Hongxia" uniqKey="Wang H" first="Hongxia" last="Wang">Hongxia Wang</name></author><author><name sortKey="Zhou, Dongsheng" sort="Zhou, Dongsheng" uniqKey="Zhou D" first="Dongsheng" last="Zhou">Dongsheng Zhou</name></author><author><name sortKey="Zhai, Junhui" sort="Zhai, Junhui" uniqKey="Zhai J" first="Junhui" last="Zhai">Junhui Zhai</name></author><author><name sortKey="Du, Zongmin" sort="Du, Zongmin" uniqKey="Du Z" first="Zongmin" last="Du">Zongmin Du</name></author><author><name sortKey="Li, Bei" sort="Li, Bei" uniqKey="Li B" first="Bei" last="Li">Bei Li</name></author><author><name sortKey="Qiu, Maofeng" sort="Qiu, Maofeng" uniqKey="Qiu M" first="Maofeng" last="Qiu">Maofeng Qiu</name></author><author><name sortKey="Han, Yanping" sort="Han, Yanping" uniqKey="Han Y" first="Yanping" last="Han">Yanping Han</name></author><author><name sortKey="Guo, Zhaobiao" sort="Guo, Zhaobiao" uniqKey="Guo Z" first="Zhaobiao" last="Guo">Zhaobiao Guo</name></author><author><name sortKey="Yang, Ruifu" sort="Yang, Ruifu" uniqKey="Yang R" first="Ruifu" last="Yang">Ruifu Yang</name></author></analytic><series><title level="j">Clinical chemistry</title><idno type="ISSN">0009-9147</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antigens, Viral (genetics)</term><term>Antigens, Viral (immunology)</term><term>Cloning, Molecular</term><term>DNA, Complementary (genetics)</term><term>Epitopes</term><term>Escherichia coli (metabolism)</term><term>Humans</term><term>Nucleocapsid Proteins (biosynthesis)</term><term>Nucleocapsid Proteins (genetics)</term><term>Nucleocapsid Proteins (immunology)</term><term>Protein Array Analysis</term><term>SARS Virus (immunology)</term><term>SARS Virus (isolation & purification)</term><term>Severe Acute Respiratory Syndrome (diagnosis)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ADN complémentaire (génétique)</term><term>Analyse par réseau de protéines</term><term>Antigènes viraux (génétique)</term><term>Antigènes viraux (immunologie)</term><term>Clonage moléculaire</term><term>Escherichia coli (métabolisme)</term><term>Humains</term><term>Protéines nucléocapside (biosynthèse)</term><term>Protéines nucléocapside (génétique)</term><term>Protéines nucléocapside (immunologie)</term><term>Syndrome respiratoire aigu sévère (diagnostic)</term><term>Virus du SRAS (immunologie)</term><term>Virus du SRAS (isolement et purification)</term><term>Épitopes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Nucleocapsid Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Antigens, Viral</term><term>DNA, Complementary</term><term>Nucleocapsid Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antigens, Viral</term><term>Nucleocapsid Proteins</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Protéines nucléocapside</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN complémentaire</term><term>Antigènes viraux</term><term>Protéines nucléocapside</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes viraux</term><term>Protéines nucléocapside</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Escherichia coli</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Escherichia coli</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cloning, Molecular</term><term>Epitopes</term><term>Humans</term><term>Protein Array Analysis</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse par réseau de protéines</term><term>Clonage moléculaire</term><term>Humains</term><term>Épitopes</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The widespread threat of severe acute respiratory syndrome (SARS) to human health has made urgent the development of fast and accurate analytical methods for its early diagnosis and a safe and efficient antiviral vaccine for preventive use. For this purpose, we investigated the antigenicity of different regions of the SARS coronavirus (SARS-CoV) nucleocapsid (N) protein.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><noCountry><name sortKey="Du, Zongmin" sort="Du, Zongmin" uniqKey="Du Z" first="Zongmin" last="Du">Zongmin Du</name><name sortKey="Guo, Zhaobiao" sort="Guo, Zhaobiao" uniqKey="Guo Z" first="Zhaobiao" last="Guo">Zhaobiao Guo</name><name sortKey="Han, Yanping" sort="Han, Yanping" uniqKey="Han Y" first="Yanping" last="Han">Yanping Han</name><name sortKey="Jiang, Lingxiao" sort="Jiang, Lingxiao" uniqKey="Jiang L" first="Lingxiao" last="Jiang">Lingxiao Jiang</name><name sortKey="Li, Bei" sort="Li, Bei" uniqKey="Li B" first="Bei" last="Li">Bei Li</name><name sortKey="Pei, Decui" sort="Pei, Decui" uniqKey="Pei D" first="Decui" last="Pei">Decui Pei</name><name sortKey="Qiu, Maofeng" sort="Qiu, Maofeng" uniqKey="Qiu M" first="Maofeng" last="Qiu">Maofeng Qiu</name><name sortKey="Song, Yajun" sort="Song, Yajun" uniqKey="Song Y" first="Yajun" last="Song">Yajun Song</name><name sortKey="Wang, Hongxia" sort="Wang, Hongxia" uniqKey="Wang H" first="Hongxia" last="Wang">Hongxia Wang</name><name sortKey="Wang, Jin" sort="Wang, Jin" uniqKey="Wang J" first="Jin" last="Wang">Jin Wang</name><name sortKey="Yang, Ruifu" sort="Yang, Ruifu" uniqKey="Yang R" first="Ruifu" last="Yang">Ruifu Yang</name><name sortKey="Zhai, Junhui" sort="Zhai, Junhui" uniqKey="Zhai J" first="Junhui" last="Zhai">Junhui Zhai</name><name sortKey="Zhou, Dongsheng" sort="Zhou, Dongsheng" uniqKey="Zhou D" first="Dongsheng" last="Zhou">Dongsheng Zhou</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Chen, Zeliang" sort="Chen, Zeliang" uniqKey="Chen Z" first="Zeliang" last="Chen">Zeliang Chen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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